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Article

The Evolving Molecular Landscape and Actionable Alterations in Urologic Cancers.

Current oncology (Toronto, Ont.) - 6 Nov 2024

Antar Ryan Michael, Fawaz Christopher, Gonzalez Diego, Xu Vincent Eric, Drouaud Arthur Pierre, Krastein Jason, Pio Faozia, Murdock Andeulazia, Youssef Kirolos, Sobol Stanislav, Whalen Michael J

Abstract excerpt

The genetic landscape of urologic cancers has evolved with the identification of actionable mutations that impact diagnosis, prognosis, and therapeutic strategies. This narrative review consolidates existing literature on genetic mutations across key urologic cancers, including bladder, renal, prostate, upper tract urothelial, testicular, and penile. The review highlights mutations in DNA damage repair genes,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39590142
DOI: 10.3390/curroncol31110511
PMCID: PMC11593205

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