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Article

Clinico-pathological and epigenetic heterogeneity of diffuse gliomas with FGFR3::TACC3 fusion.

Acta neuropathologica communications - 16 Jan 2023

Métais Alice, Tauziède-Espariat Arnault, Garcia Jeremy, Appay Romain, Uro-Coste Emmanuelle, Meyronet David, Maurage Claude-Alain, Vandenbos Fanny, Rigau Valérie, Chiforeanu Dan Christian, Pallud Johan, Senova Suhan, Saffroy Raphaël, Colin Carole, Edjlali Myriam, Varlet Pascale, Figarella-Branger Dominique

Abstract excerpt

BACKGROUND: Gliomas with FGFR3::TACC3 fusion mainly occur in adults, display pathological features of glioblastomas (GB) and are usually classified as glioblastoma, IDH-wildtype. However, cases demonstrating pathological features of low-grade glioma (LGG) lead to difficulties in classification and clinical management. We report a series of 8 GB and 14 LGG with FGFR3:TACC3 fusion in order to better characterize...

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Identifiers

PMID: 36647073
DOI: 10.1186/s40478-023-01506-z
PMCID: PMC9843943

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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