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[Detection of mutations in codon 306 of the embB gene for molecular genetic characterization of clinical Mycobacterium tuberculosis strains].

Problemy tuberkuleza i boleznei legkikh - 1 Jan 2009

Afanas'ev M V, Borovskaia A D, Il'ina E N, Smirnova T G, Larionova E E, Kuz'min A V, Andreevskaia S N, Chernousova L N, Govorun V M

Abstract excerpt

A total of 254 Mycobacterium tuberculosis strains were used in the study. Among them, there were 183 ethambutol (EMB)-resistant strains, 13 multidrug resistant ones, but EMB-sensitive, and 39 strains sensitive to rifampicin (RIF), isoniazid (INZ), and EMB. All the strains were analyzed for genetic changes in three loci: embB306, rpoB, and katG/inhA promoter, which were associated with the formation of resistance...

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Source

Identifiers

PMID: 19565815

Genes

EMB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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