Article
Real-world analysis of the prognostic value of EGFR mutation detection in plasma ctDNA from patients with advanced non-small cell lung cancer.
Cancer medicine - 1 Apr 2023
Long Chaolian, Li Kun, Liu Zichen, Zhang Nana, Xing Xuya, Xu Liming, Gai Fei, Che Nanying
Abstract excerpt
BACKGROUND: The plasma sample has emerged as a promising surrogate sample for EGFR mutation detection in advanced non-small cell lung cancer (NSCLC). In clinical practice, whether EGFR variants in baseline plasma ctDNA of advanced NSCLC can predict prognosis in addition to guiding targeted therapy remains to be further explored. MATERIAL AND METHODS: In total, 315 NSCLC patients were retrospectively enrolled....
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