Article
Plasma ctDNA increases tissue NGS-based detection of therapeutically targetable mutations in lung cancers.
BMC cancer - 31 Mar 2023
Xie Jianjiang, Yao Weishen, Chen Lingxiu, Zhu Wenjun, Liu Qiang, Geng Geng, Fang Jing, Zhao Yang, Xiao Li, Huang Zhenhua, Zhao Jing
Abstract excerpt
BACKGROUND: Circulating tumor DNA (ctDNA) has been becoming a novel convenient and noninvasive method for dynamically monitoring landscape of genomic information to guild personalized cancer treatment. In this study we comprehensively evaluated the additional value of plasma ctDNA to routine tissue next generation sequencing (NGS) of therapeutically targetable mutations in lung cancers. METHODS: The tumor tissues...
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