Article
Use of SuperARMS EGFR Mutation Detection Kit to Detect EGFR in Plasma Cell-free DNA of Patients With Lung Adenocarcinoma.
Clinical lung cancer - 1 May 2018
Cui Shaohua, Ye Lin, Wang Huimin, Chu Tianqing, Zhao Yizhuo, Gu Aiqin, Xiong Liwen, Shi Chunlei, Jiang Liyan
Abstract excerpt
BACKGROUND: The SuperARMS EGFR Mutation Detection Kit (SuperARMS) is highly selective and sensitive and able to detect 41 of the most common somatic mutations in exons 18 to 21 of the epidermal growth factor receptor gene (EGFR). It allows for the detection of 0.2% to 0.8% mutant DNA in a background of 99.8% to 99.2% normal DNA. The present study assessed the performance of SuperARMS in detecting EGFR mutations...
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