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Article

Correlation of circulating tumor DNA EGFR mutation levels with clinical outcomes in patients with advanced lung adenocarcinoma.

Chinese medical journal - 30 Sept 2021

Liu Xiang-Liang, Bai Ri-Lan, Chen Xiao, Zhao Yu-Guang, Wang Xu, Ma Ke-Wei, Tian Hui-Min, Han Fu-Jun, Liu Zi-Ling, Yang Lei, Li Wei, Gai Fei, Cui Jiu-Wei

Abstract excerpt

BACKGROUND: Circulating tumor DNA (ctDNA) is a promising biomarker for non-invasive epidermal growth factor receptor mutations (EGFRm) detection in lung cancer patients, but existing methods have limitations in sensitivity and availability. In this study, we used the ΔCt value (mutant cycle threshold [Ct] value-internal control Ct value) generated during the polymerase chain reaction (PCR) assay to convert...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34669636
DOI: 10.1097/CM9.0000000000001760
PMCID: PMC8654465

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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