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Article

Potential Impact of Pharmacogenomic Single Nucleotide Variants in a Rural Caucasian Population.

The journal of applied laboratory medicine - 6 Mar 2023

Williams Grace R, Tsongalis Gregory J, Lewis Lionel D, Barney Rachael E, Cook Leanne J, Aaron Geno K, Nerenz Robert D

Abstract excerpt

BACKGROUND: In the US adverse drug reactions (ADRs) are estimated to cause 100 000 fatalities and cost over $136 billion annually. A patient's genes play a significant role in their response to a drug. Pharmacogenomics aims to optimize drug choice and dose for individual patients by characterizing patients' pharmacologically relevant genes to identify variants of known impact. METHODS: DNA was extracted from...

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Identifiers

PMID: 36611001
DOI: 10.1093/jalm/jfac091
PMCID: PMC10539040

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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