Article
Potentially functional polymorphisms in the LIN28B gene contribute to neuroblastoma susceptibility in Chinese children.
Journal of cellular and molecular medicine - 1 Aug 2016
He Jing, Yang Tianyou, Zhang Ruizhong, Zhu Jinhong, Wang Fenghua, Zou Yan, Xia Huimin
Abstract excerpt
UNLABELLED: Neuroblastoma is the most commonly diagnosed solid tumour outside the central nervous system in children. However, genetic factors underlying neuroblastoma remain largely unclear. Previous genome-wide association study indicated that lin-28 homolog B (LIN28B) might play an important role in the development of neuroblastoma and also contributed to its poor overall survival. With the purpose to evaluate...
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