Article
estMOI: estimating multiplicity of infection using parasite deep sequencing data.
Bioinformatics (Oxford, England) - 1 May 2014
Assefa Samuel A, Preston Mark D, Campino Susana, Ocholla Harold, Sutherland Colin J, Clark Taane G
Abstract excerpt
Individuals living in endemic areas generally harbour multiple parasite strains. Multiplicity of infection (MOI) can be an indicator of immune status and transmission intensity. It has a potentially confounding effect on a number of population genetic analyses, which often assume isolates are clo...
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