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Cellular and Transcriptional Heterogeneity in the Intrahepatic Biliary Epithelium

5 Aug 2022

Abstract excerpt

Epithelial tissues comprise heterogeneous cellular subpopulations, which often compartmentalize specialized functions like absorption and secretion to distinct cell types. In the liver, hepatocytes and biliary epithelial cells (BECs; also called cholangiocytes) are the two major epithelial lineages and play distinct roles in (1) metabolism, protein synthesis, detoxification, and (2) bile transport and...

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PMID: 36593993
DOI: 10.1016/j.gastha.2022.07.015

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