Article

Understanding regional diversity in the human biliary tree through transcriptomic profiling of primary tissues and in vitro derived organoids

2019-01-01

Abstract excerpt

The biliary tree is a series of ductular tissues responsible for the drainage of bile produced by the liver and pancreatic secretions from the pancreas. The biliary tree is affected by a diversity of life- threatening diseases collectively called cholangiopathies. Cholangiopathies show regionalization, with some diseases such as biliary atresia predominantly targeting extrahepatic bile ducts (EHBDs) outside of the...

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Literature Corpus work: 88757027-39c8-576d-92b1-2920022f66b0
DOI: 10.17863/cam.33331

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