Article
Analysis of Congenital Heart Defects in Mouse Embryos Using Qualitative and Quantitative Histological Methods.
Journal of visualized experiments : JoVE - 10 Mar 2020
Ball Kristen, Kinne Renee, Aguirre Aitor
Abstract excerpt
Congenital heart defects (CHD) are the most common type of birth defect in humans, affecting up to 1% of all live births. However, the underlying causes for CHD are still poorly understood. The developing mouse constitutes a valuable model for the study of CHD, because cardiac developmental programs between mice and humans are highly conserved. The protocol describes in detail how to produce mouse embryos of the...
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