Article
Mouse models of congenital cardiovascular disease.
Current topics in developmental biology - 1 Jan 2008
Moon Anne
Abstract excerpt
Congenital heart defects occur in nearly 1% of human live births and many are lethal if not surgically repaired. In addition, the genetic contribution to congenital or acquired cardiovascular diseases that are silent at birth, but progress to cause significant disease in later life is being increasingly appreciated. Heart development and structure are highly conserved between mouse and human. The discoveries that...
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