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Article

Genome Editing and Myocardial Development.

Advances in experimental medicine and biology - 1 Jan 2023

Turan Sifa, Chaillet J Richard, Stapleton Margaret C, Wu Yijen L

Abstract excerpt

Congenital heart disease (CHD) has a strong genetic etiology, making it a likely candidate for therapeutic intervention using genetic editing. Complex genetics involving an orchestrated series of genetic events and over 400 genes are responsible for myocardial development. Cooperation is required from a vast series of genetic networks, and mutations in such can lead to CHD and cardiovascular abnormalities,...

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PMID: 36454459
DOI: 10.1007/978-981-19-5642-3_4

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