Article
Tendon properties in a mouse model of severe osteogenesis imperfecta.
Connective tissue research - 1 May 2023
Sinkam Larissa, Boraschi-Diaz Iris, Svensson René B, Kjaer Michael, Komarova Svetlana V, Bergeron Raynald, Rauch Frank, Veilleux Louis-Nicolas
Abstract excerpt
PURPOSE/AIM OF THE STUDY: Osteogenesis imperfecta is a heritable bone disorder that is usually caused by mutations in collagen type I encoding genes. The impact of such mutations on tendons, a structure with high collagen type I content, remains largely unexplored. We hypothesized that tendon properties are abnormal in the context of a mutation affecting collagen type I. The main purpose of the study was to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.