Article
Variability in tendon and knee joint biomechanics among inbred mouse strains.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Jun 2006
Wang Vincent M, Banack Trevor M, Tsai Christine W, Flatow Evan L, Jepsen Karl J
Abstract excerpt
Hereditary factors are thought to be responsible for impaired tendon function and joint laxity. The present study investigated the genotypic variability of knee laxity and stiffness and tendon mechanical and geometric properties among 16-week-old female A/J, C57BL/6J (B6), and C3H/HeJ (C3H) inbred mice. In one group of mice, knee mechanics were quantified using a custom loading apparatus enabling translation of...
Topics
- Achilles Tendon
- Animals
- Biomechanical Phenomena
- Female
- Genetic Variation
- Genotype
- Joint Instability
- Mice
- Mice, Inbred Strains
- Models, Animal
- Models, Genetic
- Phenotype
- Stifle
- Tendons
