Article
SARS-CoV-2 variants infectivity prediction and therapeutic peptide design using computational approaches.
Journal of biomolecular structure & dynamics - 1 Dec 2023
Abhinand Chandran S, Prabhakaran Athira A, Krishnamurthy Anand, Raju Rajesh, Keshava Prasad Thottethodi Subrahmanya, Nair Achuthsankar S, Rajasekharan Kallikat N, Oommen Oommen V, Sudhakaran Perumana R
Abstract excerpt
The outbreak of severe acute respiratory coronavirus 2 (SARS-CoV-2) has created a public health emergency globally. SARS-CoV-2 enters the human cell through the binding of the spike protein to human angiotensin converting enzyme 2 (ACE2) receptor. Significant changes have been reported in the mutational landscape of SARS-CoV-2 in the receptor binding domain (RBD) of S protein, subsequent to evolution of the...
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