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Article

Circulating tumor DNA as a powerful tool in diagnostics and treatment outcome prediction - focus on large B-cell lymphomas and follicular lymphomas.

Expert review of molecular diagnostics - 1 Jun 2025

Hamova Iva, Maco Maria, Tkachenko Anton, Kupcova Kristyna, Velasova Adriana, Trneny Marek, Mocikova Heidi, Havranek Ondrej

Abstract excerpt

INTRODUCTION: Pathogenesis of large B-cell lymphomas (LBCL) and follicular lymphomas (FL) is a multistep process associated with the development of diverse DNA alterations and consequent deregulation of critical cellular processes. Detection of tumor-associated mutations within non-tumor compartments (mainly plasma) is the basis of the 'liquid biopsy' concept. Apart from tumor mutational profiling, quantitative...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40326242
DOI: 10.1080/14737159.2025.2500659

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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