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A transposable element into the human long noncoding RNA CARMEN is a switch for cardiac precursor cell specification

20 Dec 2022

Abstract excerpt

AIMS: The major cardiac cell types composing the adult heart arise from common multipotent precursor cells. Cardiac lineage decisions are guided by extrinsic and cell-autonomous factors, including recently discovered long noncoding RNAs (lncRNAs). The human lncRNA CARMEN, which is known to dictate specification toward the cardiomyocyte (CM) and the smooth muscle cell (SMC) fates, generates a diversity of...

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PMID: 36537036
DOI: 10.1093/cvr/cvac191

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