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Article

Genetic influences of the effect of circulating inflammatory cytokines on osteoarthritis in humans

15 Dec 2022

Abstract excerpt

OBJECTIVE: The causal relationship between inflammatory cytokines and Osteoarthritis (OA) has not been well investigated. This study investigated the causal role of inflammatory cytokines in the risk of OA and total joint arthroplasty using the Mendelian randomization (MR) method. METHOD: Single nucleotide polymorphisms (SNPs) robustly associated with inflammatory cytokines were used as instrumental variables....

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PMID: 36529415
DOI: 10.1016/j.joca.2022.12.007

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