Article
From degenerative disease to malignant tumors: Insight to the function of ApoE.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Feb 2023
Miao Ganggang, Zhuo Danping, Han Xue, Yao Wentao, Liu Chuan, Liu Hanyuan, Cao Hongyong, Sun Yangbai, Chen Zhiqiang, Feng Tingting
Abstract excerpt
Apolipoprotein E (ApoE) is a multifunctional protein involved in lipid transport and lipoprotein metabolism, mediating lipid distribution/redistribution in tissues and cells. It can also regulate inflammation and immune function, maintain cytoskeleton stability, and improve neural tissue Function. Due to genetic polymorphisms of ApoE (ε2, ε3, and ε4), its three common structural isoforms (ApoE2, ApoE3, ApoE4) are...
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