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Causal relationship between basal metabolic rate and kidney function: a bidirectional two-sample mendelian randomization study.

Frontiers in endocrinology - 1 Jan 2024

Zhou Chaomin, Peng Yanzhe, Zhan Lin, Zha Yan

Abstract excerpt

Background: The relationship between basal metabolic rate (BMR) and Chronic kidney disease (CKD) remains unclear and controversial. In this study, we investigated the causal role of BMR in renal injury, and inversely, whether altered renal function causes changes in BMR. Methods: In this two-sample mendelian randomization (MR) study, Genetic data were accessed from published genome-wide association studies (GWAS)...

Topics

Humans
Mendelian Randomization Analysis
Glomerular Filtration Rate
Genome-Wide Association Study
Renal Insufficiency, Chronic
Basal Metabolism
Kidney
Polymorphism, Single Nucleotide
Kidney Function Tests
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38726345
DOI: 10.3389/fendo.2024.1319753
PMCID: PMC11079271

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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