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Article

Association between gut microbiota and longevity: a genetic correlation and mendelian randomization study.

BMC microbiology - 13 Dec 2022

He Dan, Liu Li, Zhang Zhen, Yang Xuena, Jia Yumeng, Wen Yan, Cheng Shiqiang, Meng Peilin, Li Chun'e, Zhang Huijie, Pan Chuyu, Zhang Feng

Abstract excerpt

BACKGROUND: Longevity is one of the most complex phenotypes, and its genetic basis remains unclear. This study aimed to explore the genetic correlation and potential causal association between gut microbiota and longevity. RESULTS: Linkage disequilibrium score (LDSC) regression analysis and a bi-directional two-sample Mendelian Randomization (MR) analysis were performed to analyze gut microbiota and...

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Identifiers

PMID: 36510142
DOI: 10.1186/s12866-022-02703-x
PMCID: PMC9746102

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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