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Article

Genetic association of the gut microbiota with epigenetic clocks mediated by inflammatory cytokines: a Mendelian randomization analysis.

Frontiers in immunology - 1 Jan 2024

Tian Siyu, Liao Xingyu, Chen Siqi, Wu Yu, Chen Min

Abstract excerpt

Background: A new aging biomarker epigenetic clock has been developed. There exists a close link between aging and gut microbiota, which may be mediated by inflammatory cytokines. However, the relationship between the epigenetic clock, gut microbiota, and the mediating substances is unclear. Methods: Two large genome-wide association meta-analyses were analyzed by two-sample Mendelian randomization. The results...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38903525
DOI: 10.3389/fimmu.2024.1339722
PMCID: PMC11186987

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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