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Mendelian randomization analyses support causal relationships between gut microbiome and longevity

15 Nov 2024

Abstract excerpt

BACKGROUND: Gut microbiome plays a significant role in longevity, and dysbiosis is indeed one of the hallmarks of aging. However, the causal relationship between gut microbiota and human longevity or aging remains elusive. METHODS: Our study assessed the causal relationships between gut microbiome and longevity using Mendelian Randomization (MR). Summary statistics for the gut microbiome were obtained from four...

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PMID: 39548551
DOI: 10.1186/s12967-024-05823-2

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