Article
Treatment of Richter's syndrome.
Hematology. American Society of Hematology. Education Program - 9 Dec 2022
Thompson Philip A, Siddiqi Tanya
Abstract excerpt
Richter's syndrome (RS) is an aggressive histologic transformation of chronic lymphocytic leukemia (CLL), most commonly to diffuse large B-cell lymphoma (DLBCL). Outcomes are generally poor, with complete remission (CR) rates of only about 20% and less than 20% long-term survival with chemoimmunotherapy (CIT). RS is biologically heterogeneous, and in 80% of patients with CLL who develop DLBCL, the disease is...
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