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Article

Addressing the challenges of accelerated and blast phase myeloproliferative neoplasms in 2022 and beyond.

Blood reviews - 1 Sept 2022

Saha Chandan, Attwell Luke, Harrison Claire N, McLornan Donal P

Abstract excerpt

Accelerated and blast phase myeloproliferative neoplasms present many challenges despite the advent of more novel and targeted therapeutic approaches. Outcome following transformation is frequently dismal, and the only curative approach remains allogeneic stem cell transplantation, applicable to a relatively small proportion of cases. Historically, potential risk factors for transformation from chronic phase...

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Identifiers

PMID: 35241294
DOI: 10.1016/j.blre.2022.100947

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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