Article
Epigenetic alterations in glioblastomas: Diagnostic, prognostic and therapeutic relevance.
International journal of cancer - 1 Aug 2023
Montella Liliana, Cuomo Mariella, Del Gaudio Nunzio, Buonaiuto Michela, Costabile Davide, Visconti Roberta, Di Risi Teodolinda, Vinciguerra Roberta, Trio Federica, Ferraro Sara, Bove Guglielmo, Facchini Gaetano, Altucci Lucia, Chiariotti Lorenzo, Della Monica Rosa
Abstract excerpt
Glioblastoma, the most common and heterogeneous tumor affecting brain parenchyma, is dismally characterized by a very poor prognosis. Thus, the search of new, more effective treatments is a vital need. Here, we will review the druggable epigenetic features of glioblastomas that are, indeed, currently explored in preclinical studies and in clinical trials for the development of more effective, personalized...
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