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Transcriptomic reveals the ferroptosis features of host response in a mouse model of Zika virus infection

8 Dec 2022

Abstract excerpt

Abstract Zika virus (ZIKV) is a neurotropic flavivirus. The outbreak of ZIKV in 2016 created a global health emergency. However, the underlying pathogenic mechanisms remain elusive. We investigated the host response features of in vivo replication in a mouse model of ZIKV infection, by performing a series of transcriptomic and bioinformatic analyses of ZIKV and mock‐infected brain tissue. Tissue damage,...

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PMID: 36477858
DOI: 10.1002/jmv.28386

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