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Molecular Mechanisms of Ferroptosis and Its Role in Viral Pathogenesis

1 Dec 2023

Abstract excerpt

Ferroptosis is a novelty form of regulated cell death, and it is mainly characterized by iron accumulation and lipid peroxidation in the cells. Its underlying mechanism is related to the amino acid, iron, and lipid metabolisms. During viral infection, pathogenic microorganisms have evolved to interfere with ferroptosis, and ferroptosis is often manipulated by viruses to regulate host cell servicing for viral...

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PMID: 38140616
DOI: 10.3390/v15122373

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