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Article

Determination of system level alterations in host transcriptome due to Zika virus (ZIKV) Infection in retinal pigment epithelium

19 Jul 2018

Abstract excerpt

Previously, we reported that Zika virus (ZIKV) causes ocular complications such as chorioretinal atrophy, by infecting cells lining the blood-retinal barrier, including the retinal pigment epithelium (RPE). To understand the molecular basis of ZIKV-induced retinal pathology, we performed a meta-analysis of transcriptome profiles of ZIKV-infected human primary RPE and other cell types infected with either ZIKV or...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30046058
DOI: 10.1038/s41598-018-29329-2

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