Article

Zika virus infection induces IL-1β-mediated inflammatory responses by macrophages in the brain of an adult mouse model

2023-01-06

Abstract excerpt

During the 2015/16 Zika virus (ZIKV) epidemic, ZIKV associated neurological diseases were reported in adults, including microcephaly, Guillain-Barre syndrome, myelitis, meningoencephalitis, and fatal encephalitis. However, the mechanisms underlying the neuropathogenesis of ZIKV infection are not yet fully understood. In this study, we used an adult ZIKV-infection mouse model ( Ifnar1 −/− ) to investigate the mech...

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Literature Corpus work: 67cc907b-9cea-5851-9fe9-5fcfa61d7c41
DOI: 10.1101/2023.01.05.522967

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