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Article

A functional Notch–survivin gene signature in basal breast cancer

24 Nov 2008

Abstract excerpt

INTRODUCTION: Basal-type, or triple-negative, breast cancer (lacking estrogen receptor, progesterone receptor, and human epidermal growth factor receptor-2 expression) is a high-risk disease for which no molecular therapies are currently available. We studied genetic signatures of basal breast cancer potentially suitable for therapeutic intervention. METHODS: We analyzed protein expression of the Notch-1...

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PMID: 19025652
DOI: 10.1186/bcr2200

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