Article
P2X3-P2X7 SNPs and gene-gene and gene-environment interactions on pediatric asthma.
The Journal of asthma : official journal of the Association for the Care of Asthma - 1 Jul 2023
Li Lingxue, Wei Bing, Jia Jingjing, Li Mo, Ren Mengyang, Zhang Shinan
Abstract excerpt
BACKGROUND: To investigate the relationship between polymorphisms of P2X3, P2X7 genes and environment interaction with susceptibility of childhood asthma. METHODS: We conducted a matched case-control study with 170 cases and 175 healthy controls. The rs10896611, rs2276038, rs3781899 in P2X3 and rs1718119, rs3751143 in P2X7 polymorphisms were genotyped using the technique of an improved multiplex ligation...