Article
Exhaustive mutational analysis of severe acute respiratory syndrome coronavirus 2 ORF3a: An essential component in the pathogen's infectivity cycle.
Protein science : a publication of the Protein Society - 1 Jan 2023
Benazraf Amit, Arkin Isaiah T
Abstract excerpt
Detailed knowledge of a protein's key residues may assist in understanding its function and designing inhibitors against it. Consequently, such knowledge of one of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)'s proteins is advantageous since the virus is the etiological agent behind one of the biggest health crises of recent times. To that end, we constructed an exhaustive library of bacteria...
Topics
- Humans
- Amino Acid Sequence
- COVID-19
- Mutagenesis
- Mutation
- SARS-CoV-2
- Viroporin Proteins
- Open Reading Frames
