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Article

Pathogenic perspective of missense mutations of ORF3a protein of SARS-CoV-2.

Virus research - 15 Jul 2021

Hassan Sk Sarif, Attrish Diksha, Ghosh Shinjini, Choudhury Pabitra Pal, Roy Bidyut

Abstract excerpt

One of the most important proteins for COVID-19 pathogenesis in SARS-CoV-2 is the ORF3a which is the largest accessory protein among others coded by the SARS-CoV-2 genome. The major roles of the protein include virulence, infectivity, ion channel activity, morphogenesis, and virus release. The coronavirus, SARS-CoV-2 is mutating rapidly, therefore, critical study of mutations in ORF3a is certainly important from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33940003
DOI: 10.1016/j.virusres.2021.198441
PMCID: PMC8086268

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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