Molecular crosstalk between articular cartilage, meniscus, synovium, and subchondral bone in osteoarthritis

Abstract excerpt

Aims Osteoarthritis (OA) is a common degenerative joint disease worldwide, which is characterized by articular cartilage lesions. With more understanding of the disease, OA is considered to be a disorder of the whole joint. However, molecular communication within and between tissues during the disease process is still unclear. In this study, we used transcriptome data to reveal crosstalk between different tissues...

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