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Article

Comprehensive Analysis of Key Genes, Signaling Pathways and miRNAs in Human Knee Osteoarthritis: Based on Bioinformatics

23 Aug 2021

Abstract excerpt

Background: Osteoarthritis (OA) is one of the main causes of disability in the elderly population, accompanied by a series of underlying pathologic changes, such as cartilage degradation, synovitis, subchondral bone sclerosis, and meniscus injury. The present study aimed to identify key genes, signaling pathways, and miRNAs in knee OA associated with the entire joint components, and to explain the potential...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34497524
DOI: 10.3389/fphar.2021.730587

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