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Article

A Functional Polymorphism in the Promoter of miR-17-92 is Associated with a Reduced Risk of Cervical Squamous Cell Carcinoma.

Reproductive sciences (Thousand Oaks, Calif.) - 1 Jan 2020

Huang Juan, Ni Shanshan, Tang Rong

Abstract excerpt

miR-17-92 cluster was differentially expressed in cervical cancer, playing an important role in regulating cell proliferation, apoptosis, migration, and invasion. The purpose of this study was to investigate the association between polymorphisms (i.e., rs9588884, rs982873, and rs1813389) in the promoter of miR-17-92 and the risk of cervical squamous cell carcinoma (CSCC). The rs9588884 polymorphism was genotyped...

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Share to Carcinoma, Squamous Cell
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Share to Promoter Regions, Genetic
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Share to Uterine Cervical Neoplasms

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PMID: 32046383
DOI: 10.1007/s43032-019-00007-6

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