Article
A pilot study to evaluate tissue- and plasma-based DNA driver mutations in a cohort of patients with pancreatic intraductal papillary mucinous neoplasms.
G3 (Bethesda, Md.) - 9 Feb 2023
Park Margaret A, Zaw Thinzar, Yoder Sean J, Gomez Maria, Genilo-Delgado Maria, Basinski Toni, Katende Esther, Dam Aamir, Mok Shaffer R S, Monteiro Alvaro, Mohammadi Amir, Jeong Daniel K, Jiang Kun, Centeno Barbara A, Hodul Pamela, Malafa Mokenge, Fleming Jason, Chen Dung-Tsa, Mo Qianxing, Teer Jamie K, Permuth Jennifer B
Abstract excerpt
Intraductal papillary mucinous neoplasms (IPMNs) are precursor lesions to pancreatic ductal adenocarcinoma that are challenging to manage due to limited imaging, cytologic, and molecular markers that accurately classify lesions, grade of dysplasia, or focus of invasion preoperatively. The objective of this pilot study was to determine the frequency and type of DNA mutations in a cohort of surgically resected,...
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