Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Added Value of Next Generation over Sanger Sequencing in Kenyan Youth with Extensive HIV-1 Drug Resistance.

Microbiology spectrum - 21 Dec 2022

Novitsky V, Nyandiko W, Vreeman R, DeLong A K, Manne A, Scanlon M, Ngeresa A, Aluoch J, Sang F, Ashimosi C, Jepkemboi E, Orido M, Hogan J W, Kantor R

Abstract excerpt

HIV-1 drug resistance testing in children and adolescents in low-resource settings is both important and challenging. New (more sensitive) drug resistance testing technologies may improve clinical care, but evaluation of their added value is limited. We assessed the potential added value of using next-generation sequencing (NGS) over Sanger sequencing for detecting nucleoside reverse transcriptase inhibitor...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-HIV Agents
Share to Drug Resistance, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to High-Throughput Nucleotide Sequencing

Share to HIV Infections

Share to Reverse Transcriptase Inhibitors

Share to Viral Load

Source

Open in PubMed Open full text

Identifiers

PMID: 36445146
DOI: 10.1128/spectrum.03454-22
PMCID: PMC9769539

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Added Value of Next Generation over Sanger Sequencing in Kenyan Youth with Extensive HIV-1 Drug Resistance.PMID 36445146Read ↗

Added Value of Next Generation Sequencing in Characterizing the Evolution of HIV-1 Drug Resistance in Kenyan Youth.Semantic proximity Read ↗

HIV-1 Drug Resistance Detected by Next-Generation Sequencing among ART-Naïve Individuals: A Systematic Review and Meta-Analysis.Semantic proximity Read ↗

The Sensitivity and Consistency Comparison Between Next-Generation Sequencing and Sanger Sequencing in HIV-1 Drug Resistance Testing for Pre-Treated PatientsSemantic proximity Read ↗

Towards Next-Generation Sequencing for HIV-1 Drug Resistance Testing in a Clinical Setting.Semantic proximity Read ↗

HIV-1 Drug Resistance Genotyping in Resource Limited Settings: Current and Future Perspectives in Sequencing Technologies.Semantic proximity Read ↗

Transmission of HIV drug resistance: lessons from sensitive screening assays.Semantic proximity Read ↗

A Sensitivity and Consistency Comparison Between Next-Generation Sequencing and Sanger Sequencing in HIV-1 Pretreatment Drug Resistance Testing.Semantic proximity Read ↗

Technologies for HIV-1 drug resistance testing: inventory and needs.Semantic proximity Read ↗

HIV-1 genotypic drug resistance testing: digging deep, reaching wide?Semantic proximity Read ↗

Next-Generation Sequencing for HIV Drug Resistance Testing: Laboratory, Clinical, and Implementation Considerations.Semantic proximity Read ↗

Limited marginal utility of deep sequencing for HIV drug resistance testing in the age of integrase inhibitorsSemantic proximity Read ↗

Primary HIV-1 Drug Resistant Minority Variants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.