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Article

Comparison of the frequency and phenotypic profile of Mycobacterium tuberculosis-specific CD4 T cells between the site of disease and blood in pericardial tuberculosis.

Frontiers in immunology - 1 Jan 2022

Du Bruyn Elsa, Ruzive Sheena, Howlett Patrick, Jacobs Ashley J, Arlehamn Cecilia S Lindestam, Sette Alessandro, Sher Alan, Mayer-Barber Katrin D, Barber Daniel L, Mayosi Bongani, Ntsekhe Mpiko, Wilkinson Robert J, Riou Catherine

Abstract excerpt

Studies of the immune response at the site of disease in extra-pulmonary tuberculosis (EPTB) disease are scarce. In this study, we compared the cellular profile of Mycobacterium tuberculosis (Mtb)-specific T cells in pericardial fluid and peripheral blood in patients with pericardial TB (PCTB). Whole blood and pericardial fluid (PCF) samples were collected at the time of diagnostic sampling, with repeat blood...

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Identifiers

PMID: 36439130
DOI: 10.3389/fimmu.2022.1009016
PMCID: PMC9692124

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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