Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Structural evolution of Delta lineage of SARS-CoV-2.

International journal of biological macromolecules - 31 Jan 2023

Gomari Mohammad Mahmoudi, Tarighi Parastoo, Choupani Edris, Abkhiz Shadi, Mohamadzadeh Masoud, Rostami Neda, Sadroddiny Esmaeil, Baammi Soukayna, Uversky Vladimir N, Dokholyan Nikolay V

Abstract excerpt

One of the main obstacles in prevention and treatment of COVID-19 is the rapid evolution of the SARS-CoV-2 Spike protein. Given that Spike is the main target of common treatments of COVID-19, mutations occurring at this virulent factor can affect the effectiveness of treatments. The B.1.617.2 lineage of SARS-CoV-2, being characterized by many Spike mutations inside and outside of its receptor-binding domain...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to COVID-19
Share to Molecular Dynamics Simulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Protein Binding

Share to SARS-CoV-2

Share to SARS-CoV-2 and COVID-19 Research

Share to Spike Glycoprotein, Coronavirus

Share to vaccines and immunoinformatics approaches

Source

Open in PubMed Open full text

Identifiers

PMID: 36435470
DOI: 10.1016/j.ijbiomac.2022.11.227
PMCID: PMC9683856

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Structural evolution of Delta lineage of SARS-CoV-2.PMID 36435470Read ↗

Impact of B.1.617 and RBD SARS-CoV-2 variants on vaccine efficacy: An in-silico approach.Semantic proximity Read ↗

Impact of B.1.617 and RBD SARS-CoV-2 Variants on Vaccine Efficacy: An In-silico ApproachSemantic proximity Read ↗

Structural Analysis of the SARS-CoV-2 Spike N-Terminal Domain Across Wild-Type and Recent Variants: A Comparative Study.Semantic proximity Read ↗

E156G and Arg158, Phe-157/del mutation in NTD of spike protein in B.1.617.2 lineage of SARS-CoV-2 leads to immune evasion through antibody escapeSemantic proximity Read ↗

Dynamics prediction of emerging notable spike protein mutations in SARS-CoV-2 implies a need for updated vaccines.Semantic proximity Read ↗

Convergence of immune escape strategies highlights plasticity of SARS-CoV-2 spikeSemantic proximity Read ↗

D614G mutation and SARS-CoV-2: impact on S-protein structure, function, infectivity, and immunity.Semantic proximity Read ↗

Exploring B-cell epitope conservation and antigenicity shift in current COVID-19 variants: Analyzing spike-antibody interactions for therapeutic uses.Semantic proximity Read ↗

Structural basis of Omicron immune evasion: A comparative computational study of Spike protein-Antibody interactionSemantic proximity Read ↗

Molecular Level Dissection of Critical Spike Mutations in SARS‐CoV‐2 Variants of Concern (VOCs): A Simplified ReviewSemantic proximity Read ↗

Structural Comparison and Drug Screening of Spike Proteins of Ten SARS-CoV-2 VariantsSemantic proximity Read ↗

SARS-CoV-2: Recent Variants and Clinical Efficacy of Antibody-Based Therapy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.