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Structural Comparison and Drug Screening of Spike Proteins of Ten SARS-CoV-2 Variants

1 Jan 2022

Abstract excerpt

SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) has evolved many variants with stronger infectivity and immune evasion than the original strain, including Alpha, Beta, Gamma, Delta, Epsilon, Kappa, Iota, Lambda, and 21H strains. Amino acid mutations are enriched in the spike protein of SARS-CoV-2, which plays a crucial role in cell infection. However, the impact of these mutations on protein...

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PMID: 35198984
DOI: 10.34133/2022/9781758

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