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Exploring B-cell epitope conservation and antigenicity shift in current COVID-19 variants: Analyzing spike-antibody interactions for therapeutic uses.

Biochemical and biophysical research communications - 20 Dec 2024

Roy Alankar, Paul Ishani, Paul Tanwi, Dihidar Aritrika, Ray Sujay

Abstract excerpt

SARS-CoV-2, responsible for the global COVID-19 pandemic, has undergone significant genetic changes, leading to various variants impacting transmissibility, severity, and vaccine efficacy. The methodology involved evaluating SARS-CoV-2 variants designated by WHO as Variants of Interest (VOIs) and Variants Under Monitoring (VUMs). Several noteworthy mutations including G446S, K417N, T478K, E484A, N501Y, and Y505H...

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Antibodies, Neutralizing
Antibodies, Viral
COVID-19
Epitope Mapping
Epitopes, B-Lymphocyte

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Spike Glycoprotein, Coronavirus

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PMID: 39531907
DOI: 10.1016/j.bbrc.2024.150948

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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