Article
D614G mutation and SARS-CoV-2: impact on S-protein structure, function, infectivity, and immunity.
Applied microbiology and biotechnology - 1 Dec 2021
Bhattacharya Manojit, Chatterjee Srijan, Sharma Ashish Ranjan, Agoramoorthy Govindasamy, Chakraborty Chiranjib
Abstract excerpt
The progression of the COVID-19 pandemic has generated numerous emerging variants of SARS-CoV-2 on a global scale. These variants have gained evolutionary advantages, comprising high virulence and serious infectivity due to multiple spike glycoprotein mutations. As a reason, variants are demonstrating significant abilities to escape the immune responses of the host. The D614G mutation in the S-glycoprotein of...
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