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Article

Distinct high resolution genome profiles of early onset and late onset colorectal cancer integrated with gene expression data identify candidate susceptibility loci.

Molecular cancer - 6 May 2010

Berg Marianne, Agesen Trude H, Thiis-Evensen Espen, Merok Marianne A, Teixeira Manuel R, Vatn Morten H, Nesbakken Arild, Skotheim Rolf I, Lothe Ragnhild A

Abstract excerpt

BACKGROUND: Estimates suggest that up to 30% of colorectal cancers (CRC) may develop due to an increased genetic risk. The mean age at diagnosis for CRC is about 70 years. Time of disease onset 20 years younger than the mean age is assumed to be indicative of genetic susceptibility. We have compared high resolution tumor genome copy number variation (CNV) (Roche NimbleGen, 385 000 oligo CGH array) in...

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Source

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Identifiers

PMID: 20459617
DOI: 10.1186/1476-4598-9-100
PMCID: PMC2885343

Genes

CLC
LTBP4
PPAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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