Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hyperuricemia during Pregnancy Leads to a Preeclampsia-Like Phenotype in Mice.

Cells - 21 Nov 2022

Lüscher Benjamin P, Schoeberlein Andreina, Surbek Daniel V, Baumann Marc U

Abstract excerpt

Hyperuricemia is a common feature in pregnancies compromised by pre-eclampsia, a pregnancy disease characterized by hypertension and proteinuria. The role of uric acid in the pathogenesis of pre-eclampsia remains largely unclear. The aim of this study was to investigate the effect of elevated uric acid serum levels during pregnancy on maternal blood pressure and neonatal outcome using two different murine...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Pressure
Share to Hypertension
Share to Hyperuricemia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Pre-Eclampsia

Share to Pregnancy

Share to Pregnancy Complications

Share to Uric Acid

Source

Open in PubMed Open full text

Identifiers

PMID: 36429132
DOI: 10.3390/cells11223703
PMCID: PMC9688737

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hyperuricemia during Pregnancy Leads to a Preeclampsia-Like Phenotype in Mice.PMID 36429132Read ↗

Uric acid, endothelial dysfunction and pre-eclampsiaSemantic proximity Read ↗

CRISPR/Cas9 Mediated Deletion of the Uox Gene Generates a Mouse Model of Hyperuricemia with Multiple Complications.Semantic proximity Read ↗

Knockout of the urate oxidase gene provides a stable mouse model of hyperuricemia associated with metabolic disorders.Semantic proximity Read ↗

The Role of Uric Acid in Human Health: Insights from the Uricase GeneSemantic proximity Read ↗

New Models of Pregnancy-Associated Hypertension.Semantic proximity Read ↗

Current State of Preeclampsia Mouse Models: Approaches, Relevance, and StandardizationSemantic proximity Read ↗

An elevation in serum uric acid precedes the development of preeclampsiaSemantic proximity Read ↗

Complement factor H-point mutation promotes the development of preeclampsia-like phenotype with multiparity in mice.Semantic proximity Read ↗

Fetuin-A is a HIF target that safeguards tissue integrity during hypoxic stressSemantic proximity Read ↗

Inherited and acquired disorders of magnesium homeostasis.Semantic proximity Read ↗

Mammalian urea transportersSemantic proximity Read ↗

Murine Placental-Fetal Phosphate Dyshomeostasis Caused by an Xpr1 Deficiency Accelerates Placental Calcification and Restricts Fetal Growth in Late GestationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.