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Circulating tumor cells and DNA for real-time EGFR detection and monitoring of non-small-cell lung cancer.

Future oncology (London, England) - 1 Apr 2017

He Jinfeng, Tan Wei, Ma Jingping

Abstract excerpt

AIM: We investigate the suitability of circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA) in non-small-cell lung cancer management, which is challenging in conventional biopsies. MATERIALS & METHODS: We performed serial blood extraction from 120 patients of varying EGFR status. Molecular profiling was performed using droplet digital PCR and correlated to survival outcome. RESULTS: Overall, we...

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Biomarkers, Tumor
Biopsy
Carcinoma, Non-Small-Cell Lung
DNA, Neoplasm
Drug Resistance, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplasm Staging

Neoplastic Cells, Circulating

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Identifiers

PMID: 28073294
DOI: 10.2217/fon-2016-0427

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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